TY - JOUR
T1 - Oxidative stress affects the beginning of the growth of cancer cells through a variety of routes
AU - Saleh, Ebraheem Abdu Musad
AU - Al-dolaimy, F.
AU - Qasim almajidi, Yasir
AU - Baymakov, Sayfiddin
AU - kader M, Mohammed Abdul
AU - Ullah, Muhammad Ikram
AU - Abbas, Ahmed hussien R.
AU - Khlewee, Ibrahim Hammoud
AU - Bisht, Yashwant Singh
AU - Alsaalamy, Ali Hashiem
N1 - Publisher Copyright:
© 2023 Elsevier GmbH
PY - 2023/9
Y1 - 2023/9
N2 - Oxidative stress is a physiological condition that occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the cell's antioxidant defense system. ROS are highly reactive molecules that can cause damage to cellular structures such as DNA, proteins, and lipids. the regulation of ROS levels and the antioxidant defense system is crucial for cancer prevention and treatment. Strategies to enhance antioxidant defenses or induce oxidative stress selectively in cancer cells are being developed as potential therapeutic approaches. targeting oxidative stress in cancer treatment is an active area of research with several potential therapeutic approaches being investigated. Developing selective and effective therapies that target oxidative stress in cancer cells while sparing normal cells will be crucial for improving cancer treatment outcomes.
AB - Oxidative stress is a physiological condition that occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the cell's antioxidant defense system. ROS are highly reactive molecules that can cause damage to cellular structures such as DNA, proteins, and lipids. the regulation of ROS levels and the antioxidant defense system is crucial for cancer prevention and treatment. Strategies to enhance antioxidant defenses or induce oxidative stress selectively in cancer cells are being developed as potential therapeutic approaches. targeting oxidative stress in cancer treatment is an active area of research with several potential therapeutic approaches being investigated. Developing selective and effective therapies that target oxidative stress in cancer cells while sparing normal cells will be crucial for improving cancer treatment outcomes.
KW - Cancer
KW - Oxidative stress
KW - Therapeutic approaches
UR - https://www.scopus.com/pages/publications/85167777676
U2 - 10.1016/j.prp.2023.154664
DO - 10.1016/j.prp.2023.154664
M3 - Review article
C2 - 37573621
AN - SCOPUS:85167777676
SN - 0344-0338
VL - 249
JO - Pathology Research and Practice
JF - Pathology Research and Practice
M1 - 154664
ER -
