One-pot synthesis of new series 3,4,5-trisubstituted-dihydroisoxazoline derivatives via 1,3-dipolar cycloaddition of nitrile oxides with chalcones

Raad Kasim Yhya; K. M. Lokanatha Rai; Ebraheem Abdu Musad

doi:10.1007/s12039-013-0439-1

One-pot synthesis of new series 3,4,5-trisubstituted-dihydroisoxazoline derivatives via 1,3-dipolar cycloaddition of nitrile oxides with chalcones

Raad Kasim Yhya
, K. M. Lokanatha Rai
, Ebraheem Abdu Musad

University of Mysore

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We have synthesized a series of novel isoxazolines via 1,3-dipolar cycloaddition reaction. Aromatic aldoximes undergo oxidative-dehydrogenation with chloramine-T to give nitrile oxides, which were reacted with chalcones to afford of 3,4,5-trisubstituted 4,5-dihydroisoxazolines in a good yield. [Figure not available: see fulltext.]

Original language	English
Pages (from-to)	799-806
Number of pages	8
Journal	Journal of Chemical Sciences
Volume	125
Issue number	4
DOIs	https://doi.org/10.1007/s12039-013-0439-1
State	Published - Jul 2013
Externally published	Yes

Keywords

1,3-dipolar cycloaddition
aromatic aldoximes
chalcones
Isoxazoline

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10.1007/s12039-013-0439-1

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title = "One-pot synthesis of new series 3,4,5-trisubstituted-dihydroisoxazoline derivatives via 1,3-dipolar cycloaddition of nitrile oxides with chalcones",

abstract = "We have synthesized a series of novel isoxazolines via 1,3-dipolar cycloaddition reaction. Aromatic aldoximes undergo oxidative-dehydrogenation with chloramine-T to give nitrile oxides, which were reacted with chalcones to afford of 3,4,5-trisubstituted 4,5-dihydroisoxazolines in a good yield. [Figure not available: see fulltext.]",

keywords = "1,3-dipolar cycloaddition, aromatic aldoximes, chalcones, Isoxazoline",

author = "Yhya, \{Raad Kasim\} and \{Lokanatha Rai\}, \{K. M.\} and Musad, \{Ebraheem Abdu\}",

year = "2013",

month = jul,

doi = "10.1007/s12039-013-0439-1",

language = "English",

volume = "125",

pages = "799--806",

journal = "Journal of Chemical Sciences",

issn = "0974-3626",

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number = "4",

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TY - JOUR

T1 - One-pot synthesis of new series 3,4,5-trisubstituted-dihydroisoxazoline derivatives via 1,3-dipolar cycloaddition of nitrile oxides with chalcones

AU - Yhya, Raad Kasim

AU - Lokanatha Rai, K. M.

AU - Musad, Ebraheem Abdu

PY - 2013/7

Y1 - 2013/7

N2 - We have synthesized a series of novel isoxazolines via 1,3-dipolar cycloaddition reaction. Aromatic aldoximes undergo oxidative-dehydrogenation with chloramine-T to give nitrile oxides, which were reacted with chalcones to afford of 3,4,5-trisubstituted 4,5-dihydroisoxazolines in a good yield. [Figure not available: see fulltext.]

AB - We have synthesized a series of novel isoxazolines via 1,3-dipolar cycloaddition reaction. Aromatic aldoximes undergo oxidative-dehydrogenation with chloramine-T to give nitrile oxides, which were reacted with chalcones to afford of 3,4,5-trisubstituted 4,5-dihydroisoxazolines in a good yield. [Figure not available: see fulltext.]

KW - 1,3-dipolar cycloaddition

KW - aromatic aldoximes

KW - chalcones

KW - Isoxazoline

UR - https://www.scopus.com/pages/publications/84883650299

U2 - 10.1007/s12039-013-0439-1

DO - 10.1007/s12039-013-0439-1

M3 - Article

AN - SCOPUS:84883650299

SN - 0974-3626

VL - 125

SP - 799

EP - 806

JO - Journal of Chemical Sciences

JF - Journal of Chemical Sciences

IS - 4

ER -

One-pot synthesis of new series 3,4,5-trisubstituted-dihydroisoxazoline derivatives via 1,3-dipolar cycloaddition of nitrile oxides with chalcones

Abstract

Keywords

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