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Natural products against cancer: Review on phytochemicals from marine sources in preventing cancer

  • Adil Farooq Wali
  • , Sabhiya Majid
  • , Shabhat Rasool
  • , Samar Bassam Shehada
  • , Shahad Khalid Abdulkareem
  • , Aimen Firdous
  • , Saba Beigh
  • , Sheeba Shakeel
  • , Saima Mushtaq
  • , Imra Akbar
  • , Hassan Madhkali
  • , Muneeb U. Rehman
  • Ras Al Khaima Medical and Health Sciences University
  • Government Medical College Srinagar
  • Kerala University of Fisheries & Ocean Studies
  • CNRS
  • University of Kashmir
  • Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir
  • Jamia Hamdard University
  • Prince Sattam Bin Abdulaziz University

Research output: Contribution to journalReview articlepeer-review

142 Scopus citations

Abstract

Marine natural products have as of now been acknowledged as the most important source of bioactive substances and drug leads. Marine flora and fauna, such as algae, bacteria, sponges, fungi, seaweeds, corals, diatoms, ascidian etc. are important resources from oceans, accounting for more than 90% of the total oceanic biomass. They are taxonomically different with huge productive and are pharmacologically active novel chemical signatures and bid a tremendous opportunity for discovery of new anti-cancer molecules. The water bodies a rich source of potent molecules which improve existence suitability and serve as chemical shield against microbes and little or huge creatures. These molecules have exhibited a range of biological properties antioxidant, antibacterial, antitumour etc. In spite of huge resources enriched with exciting chemicals, the marine floras and faunas are largely unexplored for their anticancer properties. In recent past, numerous marine anticancer compounds have been isolated, characterized, identified and are under trials for human use. In this write up we have tried to compile about marine-derived compounds anticancer biological activities of diverse flora and fauna and their underlying mechanisms and the generous raise in these compounds examined for malignant growth treatment in the course of the most recent quite a long while.

Original languageEnglish
Pages (from-to)767-777
Number of pages11
JournalSaudi Pharmaceutical Journal
Volume27
Issue number6
DOIs
StatePublished - Sep 2019
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Anti-cancer
  • Corals
  • Marine
  • Marine herbs
  • Natural products
  • Seaweeds

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