Nanodelivery of Dietary Polyphenols for Therapeutic Applications

Mithun Rudrapal; Ashwini K. Mishra; Laxmi Rani; Khomendra K. Sarwa; James H. Zothantluanga; Johra Khan; Mehnaz Kamal; Santwana Palai; Atul R. Bendale; Swati G. Talele; Vasim T. Pathan; Laxmikant B. Borse; Vishnu S. Neharkar; Pravat K. Sahoo

doi:10.3390/molecules27248706

Nanodelivery of Dietary Polyphenols for Therapeutic Applications

Mithun Rudrapal, Ashwini K. Mishra, Laxmi Rani, Khomendra K. Sarwa, James H. Zothantluanga, Johra Khan, Mehnaz Kamal, Santwana Palai, Atul R. Bendale, Swati G. Talele, Vasim T. Pathan, Laxmikant B. Borse, Vishnu S. Neharkar, Pravat K. Sahoo

Pharmaceutical Chemistry

Research output: Contribution to journal › Review article › peer-review

43 Scopus citations

Abstract

Advancement in nanotechnology has unleashed the therapeutic potentials of dietary polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific drug delivery. In this review, through citation of relevant literature reports, we discuss the application of nano-pharmaceutical formulations, such as solid lipid nanoparticles, nano-emulsions, nano-crystals, nano-polymersomes, liposomes, ethosomes, phytosomes, and invasomes for dietary polyphenols. Following this, we highlight important studies concerning different combinations of nano formulations with dietary polyphenols (also known as nanophytopolyphenols). We also provide nano-formulation paradigms for enhancing the physicochemical properties of dietary polyphenols. Finally, we highlight the latest patents that were granted on nano-formulations of dietary polyphenols. Based on our review, we observe that nanosized delivery of herbal constituents, spices, and dietary supplements have the ability to improve biological processes and address issues connected with herbal treatments.

Original language	English
Article number	8706
Journal	Molecules
Volume	27
Issue number	24
DOIs	https://doi.org/10.3390/molecules27248706
State	Published - Dec 2022

Keywords

dietary polyphenols
nanodelivery
nanoformulation
nanophytomedicine
nanotechnology

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10.3390/molecules27248706

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@article{40154a9a4454451bb0c7e117c8ecea3c,

title = "Nanodelivery of Dietary Polyphenols for Therapeutic Applications",

abstract = "Advancement in nanotechnology has unleashed the therapeutic potentials of dietary polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific drug delivery. In this review, through citation of relevant literature reports, we discuss the application of nano-pharmaceutical formulations, such as solid lipid nanoparticles, nano-emulsions, nano-crystals, nano-polymersomes, liposomes, ethosomes, phytosomes, and invasomes for dietary polyphenols. Following this, we highlight important studies concerning different combinations of nano formulations with dietary polyphenols (also known as nanophytopolyphenols). We also provide nano-formulation paradigms for enhancing the physicochemical properties of dietary polyphenols. Finally, we highlight the latest patents that were granted on nano-formulations of dietary polyphenols. Based on our review, we observe that nanosized delivery of herbal constituents, spices, and dietary supplements have the ability to improve biological processes and address issues connected with herbal treatments.",

keywords = "dietary polyphenols, nanodelivery, nanoformulation, nanophytomedicine, nanotechnology",

author = "Mithun Rudrapal and Mishra, \{Ashwini K.\} and Laxmi Rani and Sarwa, \{Khomendra K.\} and Zothantluanga, \{James H.\} and Johra Khan and Mehnaz Kamal and Santwana Palai and Bendale, \{Atul R.\} and Talele, \{Swati G.\} and Pathan, \{Vasim T.\} and Borse, \{Laxmikant B.\} and Neharkar, \{Vishnu S.\} and Sahoo, \{Pravat K.\}",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors.",

year = "2022",

month = dec,

doi = "10.3390/molecules27248706",

language = "English",

volume = "27",

journal = "Molecules",

issn = "1420-3049",

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T1 - Nanodelivery of Dietary Polyphenols for Therapeutic Applications

AU - Rudrapal, Mithun

AU - Mishra, Ashwini K.

AU - Rani, Laxmi

AU - Sarwa, Khomendra K.

AU - Zothantluanga, James H.

AU - Khan, Johra

AU - Kamal, Mehnaz

AU - Palai, Santwana

AU - Bendale, Atul R.

AU - Talele, Swati G.

AU - Pathan, Vasim T.

AU - Borse, Laxmikant B.

AU - Neharkar, Vishnu S.

AU - Sahoo, Pravat K.

PY - 2022/12

Y1 - 2022/12

N2 - Advancement in nanotechnology has unleashed the therapeutic potentials of dietary polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific drug delivery. In this review, through citation of relevant literature reports, we discuss the application of nano-pharmaceutical formulations, such as solid lipid nanoparticles, nano-emulsions, nano-crystals, nano-polymersomes, liposomes, ethosomes, phytosomes, and invasomes for dietary polyphenols. Following this, we highlight important studies concerning different combinations of nano formulations with dietary polyphenols (also known as nanophytopolyphenols). We also provide nano-formulation paradigms for enhancing the physicochemical properties of dietary polyphenols. Finally, we highlight the latest patents that were granted on nano-formulations of dietary polyphenols. Based on our review, we observe that nanosized delivery of herbal constituents, spices, and dietary supplements have the ability to improve biological processes and address issues connected with herbal treatments.

AB - Advancement in nanotechnology has unleashed the therapeutic potentials of dietary polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific drug delivery. In this review, through citation of relevant literature reports, we discuss the application of nano-pharmaceutical formulations, such as solid lipid nanoparticles, nano-emulsions, nano-crystals, nano-polymersomes, liposomes, ethosomes, phytosomes, and invasomes for dietary polyphenols. Following this, we highlight important studies concerning different combinations of nano formulations with dietary polyphenols (also known as nanophytopolyphenols). We also provide nano-formulation paradigms for enhancing the physicochemical properties of dietary polyphenols. Finally, we highlight the latest patents that were granted on nano-formulations of dietary polyphenols. Based on our review, we observe that nanosized delivery of herbal constituents, spices, and dietary supplements have the ability to improve biological processes and address issues connected with herbal treatments.

KW - dietary polyphenols

KW - nanodelivery

KW - nanoformulation

KW - nanophytomedicine

KW - nanotechnology

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U2 - 10.3390/molecules27248706

DO - 10.3390/molecules27248706

M3 - Review article

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SN - 1420-3049

VL - 27

JO - Molecules

JF - Molecules

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ER -

Nanodelivery of Dietary Polyphenols for Therapeutic Applications

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