TY - JOUR
T1 - Nanoantioxidants
T2 - The Fourth Generation of Antioxidants—Recent Research Roadmap and Future Perspectives
AU - Shah, Syed Tawab
AU - Chowdhury, Zaira Zaman
AU - Simarani, Khanom
AU - Basirun, Wan Jefrey
AU - Badruddin, Irfan Anjum
AU - Hussien, Mohamed
AU - Alrobei, Hussein
AU - Kamangar, Sarfaraz
N1 - Publisher Copyright:
© 2022 by the authors.
PY - 2022/10
Y1 - 2022/10
N2 - Antioxidants work by interacting with free radicals and converting them into harmless chemicals, interfering with the progression of potentially hazardous chain reactions. Antioxidants are useful in treating illnesses induced by free radicals because they help minimize oxidative stress. Antioxidants, whether natural or synthetic, have a limited effect on cellular health and function because of their low absorption, inability to traverse cellular membrane, and disintegration during delivery. The benefits of antioxidants, both natural and synthetic, are comparable. The use of antioxidants that are covalently attached to nanoparticles, or encased in particles with a hollow center, or feature the nanomaterial encapsulation of various origins has been employed to solve these challenges to provide improved stability, slow and slow sustained release, biocompatibility, and targeted administration. This review examines the importance of metal-based antioxidants and methods for enhancing antioxidant activities based on recent studies.
AB - Antioxidants work by interacting with free radicals and converting them into harmless chemicals, interfering with the progression of potentially hazardous chain reactions. Antioxidants are useful in treating illnesses induced by free radicals because they help minimize oxidative stress. Antioxidants, whether natural or synthetic, have a limited effect on cellular health and function because of their low absorption, inability to traverse cellular membrane, and disintegration during delivery. The benefits of antioxidants, both natural and synthetic, are comparable. The use of antioxidants that are covalently attached to nanoparticles, or encased in particles with a hollow center, or feature the nanomaterial encapsulation of various origins has been employed to solve these challenges to provide improved stability, slow and slow sustained release, biocompatibility, and targeted administration. This review examines the importance of metal-based antioxidants and methods for enhancing antioxidant activities based on recent studies.
KW - DPPH
KW - nanoantioxidants
KW - nanoparticles
UR - https://www.scopus.com/pages/publications/85140879998
U2 - 10.3390/coatings12101568
DO - 10.3390/coatings12101568
M3 - Review article
AN - SCOPUS:85140879998
SN - 2079-6412
VL - 12
JO - Coatings
JF - Coatings
IS - 10
M1 - 1568
ER -