Methanodibenzo[b,f][1,5]dioxocins as Novel Glutaminase Inhibitor with Anti-Glioblastoma Potential

Chemistry

• Glutamine 100%
• Binding Energy 50%
• Condensation 50%
• IC50 50%
• Antitumor 50%
• Calorific Value 50%
• Growth Inhibition 50%
• Antiproliferative 50%
• Antimigratory 50%
• Reactive Oxygen Species 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Glioblastoma 100%
• Glutamine 33%
• Malignant Neoplasm 16%
• IC50 16%
• Cytotoxicity 16%
• Lipinski's Rule of Five 16%
• Drug Resistance 16%
• Reactive Oxygen Metabolite 16%
• Antitumor Activity 16%
• Temozolomide 16%

Biochemistry, Genetics and Molecular Biology

• Glutamine 33%
• Enzyme 16%
• Anticancer 16%
• Programmed Cell Death 16%
• Metabolic Pathway 16%
• Binding Energy 16%
• IC50 16%
• Antineoplastic Activity 16%
• Cancer Cell 16%
• Cytotoxicity 16%
• Small Molecule 16%
• Drug Resistance 16%
• Growth Inhibition 16%