Abstract
Mannich reaction of the title compound 1 with morpholine, piperidine or piperazine gave the keto-bases 2—4, respectively. Whereas, such reaction with primary amines afforded the quinazolinones 5 and 6. Compound 1 reacts with isonicotinic acid hydrazide and formalin to give 7. Schmidt reaction of 4 and 5a gave 8 and 9, respectively. Reduction of the latter afforded the 9H-pyrimido[5,4-′]azepine ring system 10. The reaction of 1 with formalin was investigated.
| Original language | English |
|---|---|
| Pages (from-to) | 483-486 |
| Number of pages | 4 |
| Journal | Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences |
| Volume | 43 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1 Apr 1988 |
| Externally published | Yes |
Keywords
- Mannich Bases of Enaminones
- Nitrogen Heterocycles
- Octahydro-9H-pyrimido[5,4-′]-azepines
- Tetrahydro-4H-[3,1]benzoxazin-5(6H)-one
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