Mannich Reaction with 1, 3-Indandione Phenylhydrazones

M. Hammouda; E. M. Afsah; H. Zoorob; M. M. Khalifa; M. T. Zimait

doi:10.1515/znb-1990-0115

Mannich Reaction with 1, 3-Indandione Phenylhydrazones

M. Hammouda
, E. M. Afsah
, H. Zoorob
, M. M. Khalifa
, M. T. Zimait

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Mannich Reaction Mannich reaction of 1, 3-indandione-l-phenylhydrazone (1) or 1, 3-diphenylhydrazone (5) with morpholine or piperazine gave the Mannich base-phenylhydrazone 2 and 3 or the diphenylhydrazone 6 and 7. respectively. Whereas, such reaction with 1 or 5 using primary amines afforded the indeno[2.1-f]-l, 2, 4-triazepin-6(2H)-one (4) or its 6-phenylhydrazone (8). respectively. Treatment of 5 with ammonium acetate and formalin afforded 9. The indeno[1.2-f]-l, 2, 4, 5-tetrazepin-10(2H)-one (11) was obtained from the 1, 2-diphenylhydrazone 10 and formaldehyde.

Original language	English
Pages (from-to)	80-82
Number of pages	3
Journal	Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Volume	45
Issue number	1
DOIs	https://doi.org/10.1515/znb-1990-0115
State	Published - 1 Jan 1990
Externally published	Yes

Keywords

Indeno[1.2-f]-l, 2.4, 5-tetrazepinone
Indeno[2.1-f]-1.2.4-triazepinone
Mannich Bases of Phenylhydrazones

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title = "Mannich Reaction with 1, 3-Indandione Phenylhydrazones",

abstract = "Mannich Reaction Mannich reaction of 1, 3-indandione-l-phenylhydrazone (1) or 1, 3-diphenylhydrazone (5) with morpholine or piperazine gave the Mannich base-phenylhydrazone 2 and 3 or the diphenylhydrazone 6 and 7. respectively. Whereas, such reaction with 1 or 5 using primary amines afforded the indeno[2.1-f]-l, 2, 4-triazepin-6(2H)-one (4) or its 6-phenylhydrazone (8). respectively. Treatment of 5 with ammonium acetate and formalin afforded 9. The indeno[1.2-f]-l, 2, 4, 5-tetrazepin-10(2H)-one (11) was obtained from the 1, 2-diphenylhydrazone 10 and formaldehyde.",

keywords = "Indeno[1.2-f]-l, 2.4, 5-tetrazepinone, Indeno[2.1-f]-1.2.4-triazepinone, Mannich Bases of Phenylhydrazones",

author = "M. Hammouda and Afsah, \{E. M.\} and H. Zoorob and Khalifa, \{M. M.\} and Zimait, \{M. T.\}",

year = "1990",

month = jan,

day = "1",

doi = "10.1515/znb-1990-0115",

language = "English",

volume = "45",

pages = "80--82",

journal = "Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences",

issn = "0932-0776",

publisher = "Walter de Gruyter GmbH",

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TY - JOUR

T1 - Mannich Reaction with 1, 3-Indandione Phenylhydrazones

AU - Hammouda, M.

AU - Afsah, E. M.

AU - Zoorob, H.

AU - Khalifa, M. M.

AU - Zimait, M. T.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - Mannich Reaction Mannich reaction of 1, 3-indandione-l-phenylhydrazone (1) or 1, 3-diphenylhydrazone (5) with morpholine or piperazine gave the Mannich base-phenylhydrazone 2 and 3 or the diphenylhydrazone 6 and 7. respectively. Whereas, such reaction with 1 or 5 using primary amines afforded the indeno[2.1-f]-l, 2, 4-triazepin-6(2H)-one (4) or its 6-phenylhydrazone (8). respectively. Treatment of 5 with ammonium acetate and formalin afforded 9. The indeno[1.2-f]-l, 2, 4, 5-tetrazepin-10(2H)-one (11) was obtained from the 1, 2-diphenylhydrazone 10 and formaldehyde.

AB - Mannich Reaction Mannich reaction of 1, 3-indandione-l-phenylhydrazone (1) or 1, 3-diphenylhydrazone (5) with morpholine or piperazine gave the Mannich base-phenylhydrazone 2 and 3 or the diphenylhydrazone 6 and 7. respectively. Whereas, such reaction with 1 or 5 using primary amines afforded the indeno[2.1-f]-l, 2, 4-triazepin-6(2H)-one (4) or its 6-phenylhydrazone (8). respectively. Treatment of 5 with ammonium acetate and formalin afforded 9. The indeno[1.2-f]-l, 2, 4, 5-tetrazepin-10(2H)-one (11) was obtained from the 1, 2-diphenylhydrazone 10 and formaldehyde.

KW - Indeno[1.2-f]-l, 2.4, 5-tetrazepinone

KW - Indeno[2.1-f]-1.2.4-triazepinone

KW - Mannich Bases of Phenylhydrazones

UR - https://www.scopus.com/pages/publications/84944508885

U2 - 10.1515/znb-1990-0115

DO - 10.1515/znb-1990-0115

M3 - Article

AN - SCOPUS:84944508885

SN - 0932-0776

VL - 45

SP - 80

EP - 82

JO - Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences

JF - Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences

IS - 1

ER -

Mannich Reaction with 1, 3-Indandione Phenylhydrazones

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Keywords

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