@inproceedings{ecdae744a5d74f54b4d2c7c6f93cb8fc,
title = "Image-based fluid dynamics analysis of left ventricle outflow tract pressure gradient after deployment transcatheter mitral valve",
abstract = "The goal of this study was to develop an image-based model to computational investigate blood flow and pressure gradients resulting from left ventricular (LV) wall motion after the implantation of a mitral valve (MV) prosthesis. Two image-based 3D models were reconstructed from multi-slice computed tomography images obtained from patients undergoing transcatheter MV replacement. Navier-Stokes equations were then used to compute the fluid motion. Outflow tract obstruction of the models with MV prosthesis were identified by calculating the difference between LV systolic and aortic pressures. It was found that computed outflow track obstruction compared well with actual obstruction data obtained from two patients. Our study indicates computational modeling can be a valuable tool to investigate the optimal placement of prosthetic valves guided by individualized anatomical data.",
author = "Yousef Alharbi and Lovell, \{Nigel H.\} and James Otton and David Muller and \{Al Abed\}, Amr and Socrates Dokos",
note = "Publisher Copyright: {\textcopyright} 2017 IEEE.; 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 ; Conference date: 11-07-2017 Through 15-07-2017",
year = "2017",
month = sep,
day = "13",
doi = "10.1109/EMBC.2017.8037788",
language = "English",
series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "4223--4226",
booktitle = "2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society",
address = "United States",
}