Hypolipidemic activity of Aerva lanata on ethylene glycol induced calcium oxalate urolithiasis in rats

  • P. Soundararajan
  • , R. Mahesh
  • , T. Ramesh
  • , V. Hazeena Begum

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The hypolipidemic activity of Aerva lanata was assessed on ethylene glycol induced calcium oxalate urolithic rats. Total lipids, total cholesterol and triglycerides levels were significantly increased in serum, liver and kidney of calcium oxalate urolithic rats. Besides, phospholipids (PL), high-density lipoproteins (HDL), low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL) levels were altered in calcium oxalate urolithic rats. On supplementation of A. lanata aqueous suspension, the above changes were reverted to near normal. These results indicate that A. lanata aqueous suspension act as a hypolipidemic agent in calcium oxalate urolithiasis.

Original languageEnglish
Pages (from-to)557-563
Number of pages7
JournalPharmacologyonline
Volume1
StatePublished - 2007
Externally publishedYes

Keywords

  • Aerva lanata
  • Calcium oxalate
  • Hypolipidemic
  • Urolithiasis

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