TY - JOUR
T1 - Harnessing chitosan-adorned liposomes for enhanced drug delivery in cancer
AU - Shaikh, Mohammad Arshad Javed
AU - Afzal, Obaid
AU - almalki, Waleed Hassan
AU - Kazmi, Imran
AU - Alzarea, Sami I.
AU - Jafar, Mohammed
AU - Saleh Altamimi, Abdulmalik
AU - Jakhmola, Vikash
AU - Anand, Krishnan
AU - Singh, Sachin Kumar
AU - Dua, Kamal
AU - Gupta, Gaurav
N1 - Publisher Copyright:
© 2023 Elsevier B.V.
PY - 2023/8
Y1 - 2023/8
N2 - Cancer is a progressive disease that is caused by a combination of factors, including one's genetics, environment, and lifestyle choices. The pillars of cancer management include chemotherapy, surgical procedures, and radiation therapy; however, a wide variety of therapeutic combinations involving these and other therapies are also utilised. Despite its low success rate, chemotherapy remains the standard gold treatment. Drug carrier systems have been developed to address major challenges such as poor drug penetration and resistance. Future drug delivery systems should be based on chitosan liposomes because of their advantages, versatility, and ease of manufacture. In this article, we'll look at how liposomes based on chitosan can be used to treat several types of cancer through several different routes. Liposomes have been used in immunotherapy, and they can be engineered to respond to photothermal therapy as well as chemotherapeutic medicines and targeted agents.
AB - Cancer is a progressive disease that is caused by a combination of factors, including one's genetics, environment, and lifestyle choices. The pillars of cancer management include chemotherapy, surgical procedures, and radiation therapy; however, a wide variety of therapeutic combinations involving these and other therapies are also utilised. Despite its low success rate, chemotherapy remains the standard gold treatment. Drug carrier systems have been developed to address major challenges such as poor drug penetration and resistance. Future drug delivery systems should be based on chitosan liposomes because of their advantages, versatility, and ease of manufacture. In this article, we'll look at how liposomes based on chitosan can be used to treat several types of cancer through several different routes. Liposomes have been used in immunotherapy, and they can be engineered to respond to photothermal therapy as well as chemotherapeutic medicines and targeted agents.
KW - Cancer
KW - Chitosan
KW - Drug delivery
KW - Immunotherapy
KW - Liposomes
UR - http://www.scopus.com/inward/record.url?scp=85160818071&partnerID=8YFLogxK
U2 - 10.1016/j.jddst.2023.104619
DO - 10.1016/j.jddst.2023.104619
M3 - Review article
AN - SCOPUS:85160818071
SN - 1773-2247
VL - 85
JO - Journal of Drug Delivery Science and Technology
JF - Journal of Drug Delivery Science and Technology
M1 - 104619
ER -