Genotypic variations around the world: Is hepatitis C virus evolving?

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Hepatitis C virus (HCV) is a major causative agent of chronic liver disease worldwide. HCV is characterized by genetic heterogeneity, with at least six genotypes identified. The geographic distribution of genotypes has shown variations in different parts of the world over the past decade because of variations in population structure, immigration, and routes of transmission. Genotype differ-ences are of epidemiologic interest and help the study of viral transmission dynamics to trace the source of HCV infection in a given population. Hepatitis C genotypes are also of considerable clinical importance because they affect response to antiviral therapy and represent a challenging obstacle for vaccine development.

Original languageEnglish
Pages (from-to)142-149
Number of pages8
JournalCurrent Hepatitis Reports
Volume5
Issue number4
DOIs
StatePublished - Oct 2006
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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