TY - JOUR
T1 - Exploring the neuroprotective benefits of phytochemicals extracted from indigenous edible fruits in Bangladesh
AU - Roy, Sumon
AU - Roy, Sajib Chandra
AU - Zehravi, Mehrukh
AU - Sweilam, Sherouk Hussein
AU - Das, Rajib
AU - Palanisamy, Mylsamy
AU - Dantinapalli, Venkata Lakshamana Sagar
AU - Elumalai, Selvaraja
AU - Gupta, Jeetendra Kumar
AU - Alshehri, Mohammed Ali
AU - Asiri, Mohammed
AU - Ahmad, Irfan
AU - Nafady, Mohamed H.
AU - Emran, Talha Bin
N1 - Publisher Copyright:
© 2024 The Author(s). Animal Models and Experimental Medicine published by John Wiley & Sons Australia, Ltd on behalf of The Chinese Association for Laboratory Animal Sciences.
PY - 2025
Y1 - 2025
N2 - The increasing incidence of neurodegenerative diseases (NDs) and the constraints of existing treatment methods have spurred a keen interest in investigating alternative therapies. Medicinal plants, renowned for their long-standing use in traditional medicine, offer a hopeful avenue for discovering new neuroprotective agents. This study emphasizes the potential neuroprotective characteristics of edible fruit plants in Bangladesh, specifically focusing on their traditional folk medicine uses for neurological disorders. This study provides an in-depth overview of the different types of edible fruit trees in Bangladesh and their phytochemicals, including flavonoids, terpenoids, and phenolic acids. This work examines the scientific data supporting the neuroprotective properties of bioactive chemicals from plants. It further explores the mechanisms by which these compounds work to counteract oxidative stress, decrease inflammation, and stimulate neurogenesis. Moreover, the study investigates toxicological characteristics and bioactive components of some fruits, emphasizing the importance of further investigation to measure their safety profile comprehensively. This thorough study highlights the potential benefits of Bangladesh's edible fruit trees as a rich source of neuroprotective chemicals. It also shows that additional research might lead to novel approaches for improving brain functioning and preventing NDs.
AB - The increasing incidence of neurodegenerative diseases (NDs) and the constraints of existing treatment methods have spurred a keen interest in investigating alternative therapies. Medicinal plants, renowned for their long-standing use in traditional medicine, offer a hopeful avenue for discovering new neuroprotective agents. This study emphasizes the potential neuroprotective characteristics of edible fruit plants in Bangladesh, specifically focusing on their traditional folk medicine uses for neurological disorders. This study provides an in-depth overview of the different types of edible fruit trees in Bangladesh and their phytochemicals, including flavonoids, terpenoids, and phenolic acids. This work examines the scientific data supporting the neuroprotective properties of bioactive chemicals from plants. It further explores the mechanisms by which these compounds work to counteract oxidative stress, decrease inflammation, and stimulate neurogenesis. Moreover, the study investigates toxicological characteristics and bioactive components of some fruits, emphasizing the importance of further investigation to measure their safety profile comprehensively. This thorough study highlights the potential benefits of Bangladesh's edible fruit trees as a rich source of neuroprotective chemicals. It also shows that additional research might lead to novel approaches for improving brain functioning and preventing NDs.
KW - Bangladesh
KW - edible fruit plants
KW - neuroprotection
KW - phytochemicals
KW - traditional medicine
UR - https://www.scopus.com/pages/publications/85215506348
U2 - 10.1002/ame2.12522
DO - 10.1002/ame2.12522
M3 - Review article
AN - SCOPUS:85215506348
SN - 2096-5451
JO - Animal Models and Experimental Medicine
JF - Animal Models and Experimental Medicine
ER -