Abstract
Advancements in the field of cancer therapeutics have witnessed a recent surge in the use of liposomes. The physicochemical characteristics of the liposomes and their components, including the lipid phase transition temperature, vesicular size and size distribution, surface properties, and route of administration, play a significant role in the modulation of the immune response as an adjuvant and for loaded antigen (Ag). Cationic liposomes, concerning their potential ability to amplify the immunogenicity of the loaded Ag/adjuvant, have received enormous interest as a promising vaccine delivery platform for cancer immunotherapy. In the present review, the physicochemical considerations for the development of Ag/adjuvant-loaded liposomes and the cationic liposomes' effectiveness for promoting cancer immunotherapy have been summarized.
| Original language | English |
|---|---|
| Pages (from-to) | 491-507 |
| Number of pages | 17 |
| Journal | Immunotherapy |
| Volume | 13 |
| Issue number | 6 |
| DOIs | |
| State | Published - Apr 2021 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
Keywords
- cancer immunotherapy
- cationic liposome
- delivery vehicle
- DOTAP
- fusogenic
- liposomal vaccine
- nanoliposome
- nanomedicine
- synthetic vaccine
- vaccine
Fingerprint
Dive into the research topics of 'Emerging advances in cationic liposomal cancer nanovaccines: Opportunities and challenges'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver