Dynamics and stability analysis of nonlinear DNA molecules: Insights from the Peyrard-Bishop model

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Abstract

This study explores the nonlinear Peyrard-Bishop DNA dynamic model, a nonlinear evolution equation that describes the behavior of DNA molecules by considering hydrogen bonds between base pairs and stacking interactions between adjacent base pairs. The primary objective is to derive analytical solutions to this model using the Khater III and improved Kudryashov methods. Subsequently, the stability of these solutions is analyzed through Hamiltonian system characterization. The Peyrard-Bishop model is pivotal in biophysics, offering insights into the dynamics of DNA molecules and their responses to external forces. By employing these analytical techniques and stability analysis, this research aims to enhance the understanding of DNA dynamics and its implications in fields such as drug design, gene therapy, and molecular biology. The novelty of this work lies in the application of the Khater III and an enhanced Kudryashov methods to the Peyrard-Bishop model, along with a comprehensive stability investigation using Hamiltonian system characterization, providing new perspectives on DNA molecule dynamics within the scope of nonlinear dynamics and biophysics.

Original languageEnglish
Pages (from-to)23449-23467
Number of pages19
JournalAIMS Mathematics
Volume9
Issue number9
DOIs
StatePublished - 2024

Keywords

  • analytical solutions
  • DNA dynamics
  • nonlinear evolution equations
  • Peyrard-Bishop model

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