TY - JOUR
T1 - Determinants of health-related quality of life among warfarin patients in Pakistan
AU - Iqbal, Muhammad Shahid
AU - Muthanna, Fares M.S.
AU - Kassab, Yaman Walid
AU - Hassali, Mohamed Azmi
AU - Al-Saikhan, Fahad I.
AU - Iqbal, Muhammad Zahid
AU - Haseeb, Abdul
AU - Ahmed, Muhammad
AU - Khan, Salah Ud Din
AU - Naqvi, Atta Abbas
AU - Islam, Md Ashraful
AU - Ali, Majid
N1 - Publisher Copyright:
© 2020 Iqbal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2020/6
Y1 - 2020/6
N2 - Introduction The effect of anticoagulation control on overall Health-Related Quality of Life (HRQoL) in patients taking warfarin in Pakistan has not been explored yet. Therefore, this study aimed to evaluate HRQoL among warfarin patients in Pakistan. Methods This cross-sectional study was conducted among patients on warfarin in Pakistan. By purposive sampling, data were collected using demographic data collection form and the World Health Organization Quality of Life: Brief Version (WHOQOL-BREF). The WHOQOL-BREF is comprised of four domains; physical, psychological, social relationships, and environment. Descriptive and inferential statistical analysis was done using SPSS version 22. Results Out of 295 warfarin patients, more females than males (<0.001) were observed (n = 184, 62.4%, and n = 111, 37.6% respectively). One hundred and eighteen (40.0%) patients were less than 30-years of age, whereas one hundred and seventy-seven (60.0%) patients were above 30-years of age. Mean scores for the physical (62.44±15.36), psychological (67.84 ±15.54), social (64.27±26.28) and environment domains (63.45±17.66) were observed. Conclusion Patients had overall lower to moderate but satisfactory HRQoL scores in all four domains. Age, gender, employment status, education level, the indication of use and duration of warfarin therapy was associated with one or more domains of HRQoL among warfarin patients. The findings of this study would serve as a primary database for future studies. This study highlights how non-clinical factors could impact HRQoL in studied patients.
AB - Introduction The effect of anticoagulation control on overall Health-Related Quality of Life (HRQoL) in patients taking warfarin in Pakistan has not been explored yet. Therefore, this study aimed to evaluate HRQoL among warfarin patients in Pakistan. Methods This cross-sectional study was conducted among patients on warfarin in Pakistan. By purposive sampling, data were collected using demographic data collection form and the World Health Organization Quality of Life: Brief Version (WHOQOL-BREF). The WHOQOL-BREF is comprised of four domains; physical, psychological, social relationships, and environment. Descriptive and inferential statistical analysis was done using SPSS version 22. Results Out of 295 warfarin patients, more females than males (<0.001) were observed (n = 184, 62.4%, and n = 111, 37.6% respectively). One hundred and eighteen (40.0%) patients were less than 30-years of age, whereas one hundred and seventy-seven (60.0%) patients were above 30-years of age. Mean scores for the physical (62.44±15.36), psychological (67.84 ±15.54), social (64.27±26.28) and environment domains (63.45±17.66) were observed. Conclusion Patients had overall lower to moderate but satisfactory HRQoL scores in all four domains. Age, gender, employment status, education level, the indication of use and duration of warfarin therapy was associated with one or more domains of HRQoL among warfarin patients. The findings of this study would serve as a primary database for future studies. This study highlights how non-clinical factors could impact HRQoL in studied patients.
UR - http://www.scopus.com/inward/record.url?scp=85086693789&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0234734
DO - 10.1371/journal.pone.0234734
M3 - Article
C2 - 32555595
AN - SCOPUS:85086693789
SN - 1932-6203
VL - 15
JO - PLoS ONE
JF - PLoS ONE
IS - 6
M1 - e0234734
ER -