Correlated Factors Affecting Health-Related Quality of Life of Patients with Chronic Obstructive Pulmonary Disease and Asthma in Jordan

Introduction: Patients with chronic obstructive pulmonary disease (COPD) and asthma often face a significant symptom burden and reduced health-related quality of life (HRQoL). Understanding the factors influencing HRQoL in this population is essential for developing effective interventions. Purpose: This study aimed to assess the perceived symptoms, physical limitations, and impacts on HRQoL among COPD and asthma patients in Jordan. Additionally, we aimed to identify factors correlated with HRQoL in this population. Methods: A cross-sectional survey was conducted among 120 patients, utilizing the St. George's Respiratory Questionnaire for COPD patients. Participants reported their recent respiratory symptoms, limitations in physical activity, and impacts on daily life. Correlation analyses were performed to investigate the associations between various factors and HRQoL. Results: The survey revealed a high prevalence of symptoms, including cough, phlegm production, breathlessness, and wheezing, with the symptoms significantly impacting patients' physical activity and overall well-being. Young age, a higher level of education, perceived excellent or very good health status, increased sleep duration, and a high Forced Expiratory Volume (FEV1) were found to be positively and significantly correlated with higher HRQoL. In contrast, smoking, higher BMI, the presence of comorbidities, a high respiratory rate, and mental health symptoms such as anxiety and depression were positively and significantly correlated with lower HRQoL. Conclusion: This study provides valuable insights into the factors affecting HRQoL among patients with COPD and asthma in Jordan. The findings underscore the need for comprehensive interventions addressing both physical and emotional aspects to improve the well-being of this patient population. Further research is warranted to explore and implement targeted interventions for enhancing HRQoL in these patients.