Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review

Faheem Anwar; Fatima Haider; Sarmir Khan; Ibrar Ahmad; Naveed Ahmed; Muhammad Imran; Summya Rashid; Zhi Guang Ren; Saadullah Khattak; Xin Ying Ji

doi:10.3390/life13020522

Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review

Faheem Anwar
, Fatima Haider
, Sarmir Khan
, Ibrar Ahmad
, Naveed Ahmed
, Muhammad Imran
, Summya Rashid
, Zhi Guang Ren
, Saadullah Khattak
, Xin Ying Ji

Pharmacology

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democratic Republic of Congo in 1970. In April 2022, several cases were recorded in widespread regions of Africa, the Northern and western hemispheres. The current review spotlights taxonomic classification, clinical presentations during infection, and the pathogenicity of the monkeypox virus in humans. Furthermore, the current review also highlights different diagnostics used for virus detection.

Original language	English
Article number	522
Journal	Life
Volume	13
Issue number	2
DOIs	https://doi.org/10.3390/life13020522
State	Published - Feb 2023

Keywords

emerging viruses
monkeypox virus
outbreak
pathogenicity
vaccination

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/life13020522

Cite this

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title = "Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review",

abstract = "Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democratic Republic of Congo in 1970. In April 2022, several cases were recorded in widespread regions of Africa, the Northern and western hemispheres. The current review spotlights taxonomic classification, clinical presentations during infection, and the pathogenicity of the monkeypox virus in humans. Furthermore, the current review also highlights different diagnostics used for virus detection.",

keywords = "emerging viruses, monkeypox virus, outbreak, pathogenicity, vaccination",

author = "Faheem Anwar and Fatima Haider and Sarmir Khan and Ibrar Ahmad and Naveed Ahmed and Muhammad Imran and Summya Rashid and Ren, \{Zhi Guang\} and Saadullah Khattak and Ji, \{Xin Ying\}",

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year = "2023",

month = feb,

doi = "10.3390/life13020522",

language = "English",

volume = "13",

journal = "Life",

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T1 - Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus

T2 - A Comprehensive Review

AU - Anwar, Faheem

AU - Haider, Fatima

AU - Khan, Sarmir

AU - Ahmad, Ibrar

AU - Ahmed, Naveed

AU - Imran, Muhammad

AU - Rashid, Summya

AU - Ren, Zhi Guang

AU - Khattak, Saadullah

AU - Ji, Xin Ying

PY - 2023/2

Y1 - 2023/2

N2 - Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democratic Republic of Congo in 1970. In April 2022, several cases were recorded in widespread regions of Africa, the Northern and western hemispheres. The current review spotlights taxonomic classification, clinical presentations during infection, and the pathogenicity of the monkeypox virus in humans. Furthermore, the current review also highlights different diagnostics used for virus detection.

AB - Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democratic Republic of Congo in 1970. In April 2022, several cases were recorded in widespread regions of Africa, the Northern and western hemispheres. The current review spotlights taxonomic classification, clinical presentations during infection, and the pathogenicity of the monkeypox virus in humans. Furthermore, the current review also highlights different diagnostics used for virus detection.

KW - emerging viruses

KW - monkeypox virus

KW - outbreak

KW - pathogenicity

KW - vaccination

UR - https://www.scopus.com/pages/publications/85148874301

U2 - 10.3390/life13020522

DO - 10.3390/life13020522

M3 - Review article

AN - SCOPUS:85148874301

SN - 2075-1729

VL - 13

JO - Life

JF - Life

IS - 2

M1 - 522

ER -

Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review

Abstract

Keywords

UN SDGs

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