Chrono-drug Delivery Systems: Timed-release Formulations

Sanket Kumar; Ahmed Abdullah Khan; Mohammad Javed Ansari; Alhussain Aodah; Ramadan I.Kh Al-shdefat

doi:10.1201/9781003637745-8

Chrono-drug Delivery Systems: Timed-release Formulations

Sanket Kumar
, Ahmed Abdullah Khan
, Mohammad Javed Ansari
, Alhussain Aodah
, Ramadan I.Kh Al-shdefat

Pharmaceutics

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Chrono-drug delivery systems (CDDS) optimize therapeutic outcomes by aligning drug release with the body's circadian rhythms. Unlike traditional methods, CDDS enable time-specific drug release to address conditions like hypertension, asthma, and arthritis, which exhibit time-dependent symptoms. Utilizing advanced formulations such as pulsatile systems and stimuli-responsive designs, CDDS enhance efficacy, reduce toxicity, and improve adherence. Technological innovations like smart materials further personalize treatments. With applications in cardiovascular, respiratory, and metabolic diseases, and potential in oncology and neurology, CDDS promise transformative advancements in precision medicine.

Original language	English
Title of host publication	Chronopharmacology
Subtitle of host publication	Time-Dependent Pharmacotherapy
Publisher	CRC Press
Pages	140-163
Number of pages	24
ISBN (Electronic)	9781040594841
ISBN (Print)	9781041067191
DOIs	https://doi.org/10.1201/9781003637745-8
State	Published - 18 Nov 2025

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10.1201/9781003637745-8

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abstract = "Chrono-drug delivery systems (CDDS) optimize therapeutic outcomes by aligning drug release with the body's circadian rhythms. Unlike traditional methods, CDDS enable time-specific drug release to address conditions like hypertension, asthma, and arthritis, which exhibit time-dependent symptoms. Utilizing advanced formulations such as pulsatile systems and stimuli-responsive designs, CDDS enhance efficacy, reduce toxicity, and improve adherence. Technological innovations like smart materials further personalize treatments. With applications in cardiovascular, respiratory, and metabolic diseases, and potential in oncology and neurology, CDDS promise transformative advancements in precision medicine.",

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AU - Khan, Ahmed Abdullah

AU - Javed Ansari, Mohammad

AU - Aodah, Alhussain

AU - Al-shdefat, Ramadan I.Kh

PY - 2025/11/18

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AB - Chrono-drug delivery systems (CDDS) optimize therapeutic outcomes by aligning drug release with the body's circadian rhythms. Unlike traditional methods, CDDS enable time-specific drug release to address conditions like hypertension, asthma, and arthritis, which exhibit time-dependent symptoms. Utilizing advanced formulations such as pulsatile systems and stimuli-responsive designs, CDDS enhance efficacy, reduce toxicity, and improve adherence. Technological innovations like smart materials further personalize treatments. With applications in cardiovascular, respiratory, and metabolic diseases, and potential in oncology and neurology, CDDS promise transformative advancements in precision medicine.

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BT - Chronopharmacology

PB - CRC Press

ER -

Chrono-drug Delivery Systems: Timed-release Formulations

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