Chemical and in vitro anti-inflammatory assessment of Echinops erinaceus

Shrouq H. Sweilam; Fatma M. Abdel Bar; Omayma D. ElGindi; Moshera M. El-Sherei; Essam A. Abdel-Sattar

doi:10.26538/tjnpr/v5i4.20

Chemical and in vitro anti-inflammatory assessment of Echinops erinaceus

Shrouq H. Sweilam, Fatma M. Abdel Bar, Omayma D. ElGindi, Moshera M. El-Sherei, Essam A. Abdel-Sattar

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Abstract

Echinops erinaceus Kit Tan is a wild plant growing in the middle regions of Saudi Arabia. From the available literature, nothing has been reported on its chemical analysis or biological activity. In this study, various extracts of Echinops erinaceus were estimated for their total phenolics, and flavonoids contents. The extracts were also evaluated for their in vitro antioxidant activity using DPPH, FRAP, and ABTS assays. Furthermore, the enzyme inhibitory activity against cyclooxygenases and 15-lipoxygenase was performed. The results showed that the polar and semi-polar extracts demonstrated considerable in vitro anti-inflammatory and antioxidant activities.

Original language	English
Pages (from-to)	715-719
Number of pages	5
Journal	Tropical Journal of Natural Product Research
Volume	5
Issue number	4
DOIs	https://doi.org/10.26538/tjnpr/v5i4.20
State	Published - Apr 2021

Keywords

Antioxidant
Asteraceae
Cyclooxygenase
Echinops erinaceus
Lipoxygenase

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10.26538/tjnpr/v5i4.20

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title = "Chemical and in vitro anti-inflammatory assessment of Echinops erinaceus",

abstract = "Echinops erinaceus Kit Tan is a wild plant growing in the middle regions of Saudi Arabia. From the available literature, nothing has been reported on its chemical analysis or biological activity. In this study, various extracts of Echinops erinaceus were estimated for their total phenolics, and flavonoids contents. The extracts were also evaluated for their in vitro antioxidant activity using DPPH, FRAP, and ABTS assays. Furthermore, the enzyme inhibitory activity against cyclooxygenases and 15-lipoxygenase was performed. The results showed that the polar and semi-polar extracts demonstrated considerable in vitro anti-inflammatory and antioxidant activities.",

keywords = "Antioxidant, Asteraceae, Cyclooxygenase, Echinops erinaceus, Lipoxygenase",

author = "Sweilam, \{Shrouq H.\} and \{Abdel Bar\}, \{Fatma M.\} and ElGindi, \{Omayma D.\} and El-Sherei, \{Moshera M.\} and Abdel-Sattar, \{Essam A.\}",

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year = "2021",

month = apr,

doi = "10.26538/tjnpr/v5i4.20",

language = "English",

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T1 - Chemical and in vitro anti-inflammatory assessment of Echinops erinaceus

AU - Sweilam, Shrouq H.

AU - Abdel Bar, Fatma M.

AU - ElGindi, Omayma D.

AU - El-Sherei, Moshera M.

AU - Abdel-Sattar, Essam A.

PY - 2021/4

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AB - Echinops erinaceus Kit Tan is a wild plant growing in the middle regions of Saudi Arabia. From the available literature, nothing has been reported on its chemical analysis or biological activity. In this study, various extracts of Echinops erinaceus were estimated for their total phenolics, and flavonoids contents. The extracts were also evaluated for their in vitro antioxidant activity using DPPH, FRAP, and ABTS assays. Furthermore, the enzyme inhibitory activity against cyclooxygenases and 15-lipoxygenase was performed. The results showed that the polar and semi-polar extracts demonstrated considerable in vitro anti-inflammatory and antioxidant activities.

KW - Antioxidant

KW - Asteraceae

KW - Cyclooxygenase

KW - Echinops erinaceus

KW - Lipoxygenase

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JO - Tropical Journal of Natural Product Research

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ER -

Chemical and in vitro anti-inflammatory assessment of Echinops erinaceus

Abstract

Keywords

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