TY - JOUR
T1 - Applications and efficacy of minoxidil in dermatology
AU - Hussein, Ramadan S.
AU - Dayel, Salman Bin
AU - Abahussein, Othman
AU - El-Sherbiny, Abeer Ali
N1 - Publisher Copyright:
© 2024 The Author(s). Skin Health and Disease published by John Wiley & Sons Ltd on behalf of British Association of Dermatologists.
PY - 2024/12
Y1 - 2024/12
N2 - Minoxidil, originally developed as an antihypertensive medication, has evolved into a versatile therapeutic agent within dermatology, notably for its effectiveness in promoting hair growth. Despite its widespread use, understanding its precise mechanism of action remains a challenge. This paper addresses this gap by providing a comprehensive review of pharmacological properties, action mechanisms, clinical effectiveness and side effects associated with topical minoxidil. Furthermore, it highlights emerging trends and applications, including its role in treating androgenetic alopecia, its potential for alopecia areata management and its utilization in combination therapies. Additionally, this paper explores novel applications in scar treatment and wound healing. By synthesizing current knowledge and insights, this review adds clarity to the diverse applications of minoxidil, providing valuable guidance for clinicians and researchers aiming to optimize its therapeutic use in dermatology.
AB - Minoxidil, originally developed as an antihypertensive medication, has evolved into a versatile therapeutic agent within dermatology, notably for its effectiveness in promoting hair growth. Despite its widespread use, understanding its precise mechanism of action remains a challenge. This paper addresses this gap by providing a comprehensive review of pharmacological properties, action mechanisms, clinical effectiveness and side effects associated with topical minoxidil. Furthermore, it highlights emerging trends and applications, including its role in treating androgenetic alopecia, its potential for alopecia areata management and its utilization in combination therapies. Additionally, this paper explores novel applications in scar treatment and wound healing. By synthesizing current knowledge and insights, this review adds clarity to the diverse applications of minoxidil, providing valuable guidance for clinicians and researchers aiming to optimize its therapeutic use in dermatology.
UR - http://www.scopus.com/inward/record.url?scp=85210040997&partnerID=8YFLogxK
U2 - 10.1002/ski2.472
DO - 10.1002/ski2.472
M3 - Review article
AN - SCOPUS:85210040997
SN - 2690-442X
VL - 4
JO - Skin Health and Disease
JF - Skin Health and Disease
IS - 6
M1 - e472
ER -