Antitumor efficacy of Curcumin nanoparticles

Eman A. Abdelmoneam; Monira M. Rageh; Ebtesam A. Mohamad

doi:10.21608/EJCHEM.2022.152966.6623

Antitumor efficacy of Curcumin nanoparticles

Eman A. Abdelmoneam, Monira M. Rageh, Ebtesam A. Mohamad

Cairo University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The present study tried to evaluate the anticancer ability of curcumin by decreasing its adverse effects and increasing its bioavailability. In this work curcumin was loaded in nano emulsions then characterized by transmission electron microscope (TEM). The antitumor efficacy of the curcumin nano emulsions was assessed in mice by DNA comet assay analysis, FTIR and examination of tumor histopathology. The obtained results found that mice treated with curcumin nano emulsions were effective in reducing DNA damage and changes in tumor tissue structure. In conclusion, curcumin nano emulsions have potential efficiency in treating tumor tissues.

Original language	English
Pages (from-to)	403-406
Number of pages	4
Journal	Egyptian Journal of Chemistry
Volume	66
Issue number	4
DOIs	https://doi.org/10.21608/EJCHEM.2022.152966.6623
State	Published - Apr 2023
Externally published	Yes

Keywords

Comet
Nano-curcumin
Tumor

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.21608/EJCHEM.2022.152966.6623

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title = "Antitumor efficacy of Curcumin nanoparticles",

abstract = "The present study tried to evaluate the anticancer ability of curcumin by decreasing its adverse effects and increasing its bioavailability. In this work curcumin was loaded in nano emulsions then characterized by transmission electron microscope (TEM). The antitumor efficacy of the curcumin nano emulsions was assessed in mice by DNA comet assay analysis, FTIR and examination of tumor histopathology. The obtained results found that mice treated with curcumin nano emulsions were effective in reducing DNA damage and changes in tumor tissue structure. In conclusion, curcumin nano emulsions have potential efficiency in treating tumor tissues.",

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T1 - Antitumor efficacy of Curcumin nanoparticles

AU - Abdelmoneam, Eman A.

AU - Rageh, Monira M.

AU - Mohamad, Ebtesam A.

PY - 2023/4

Y1 - 2023/4

N2 - The present study tried to evaluate the anticancer ability of curcumin by decreasing its adverse effects and increasing its bioavailability. In this work curcumin was loaded in nano emulsions then characterized by transmission electron microscope (TEM). The antitumor efficacy of the curcumin nano emulsions was assessed in mice by DNA comet assay analysis, FTIR and examination of tumor histopathology. The obtained results found that mice treated with curcumin nano emulsions were effective in reducing DNA damage and changes in tumor tissue structure. In conclusion, curcumin nano emulsions have potential efficiency in treating tumor tissues.

AB - The present study tried to evaluate the anticancer ability of curcumin by decreasing its adverse effects and increasing its bioavailability. In this work curcumin was loaded in nano emulsions then characterized by transmission electron microscope (TEM). The antitumor efficacy of the curcumin nano emulsions was assessed in mice by DNA comet assay analysis, FTIR and examination of tumor histopathology. The obtained results found that mice treated with curcumin nano emulsions were effective in reducing DNA damage and changes in tumor tissue structure. In conclusion, curcumin nano emulsions have potential efficiency in treating tumor tissues.

KW - Comet

KW - Nano-curcumin

KW - Tumor

UR - http://www.scopus.com/inward/record.url?scp=85164604302&partnerID=8YFLogxK

U2 - 10.21608/EJCHEM.2022.152966.6623

DO - 10.21608/EJCHEM.2022.152966.6623

M3 - Article

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SN - 0449-2285

VL - 66

SP - 403

EP - 406

JO - Egyptian Journal of Chemistry

JF - Egyptian Journal of Chemistry

IS - 4

ER -

Antitumor efficacy of Curcumin nanoparticles

Abstract

Keywords

UN SDGs

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