Antimicrobial isoflavans from Astragalus species

Nadia A. El-Sebakhy; Aya M. Asaad; Rokia M. Abdallah; Soad M. Toaima; Maged S. Abdel-Kader; Frank R. Stermitz

doi:10.1016/S0031-9422(00)89728-9

Antimicrobial isoflavans from Astragalus species

Nadia A. El-Sebakhy
, Aya M. Asaad
, Rokia M. Abdallah
, Soad M. Toaima
, Maged S. Abdel-Kader
, Frank R. Stermitz

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Two new antimicrobial isoflavans, 1-[(3R)-7,8-dimethoxybenzopyranyl]-4-hydroxybenzoquinone (astragaluquinone) and (3S)-7,1′-dihydroxy-8,3′-dimethoxyisoflavan (8-methoxyvestitol), and the known 7-hydroxy-2′,3′,4′-trimethoxyisoflavan were isolated from roots of Astragalus alexandrinus and A. trigonus. The structures of the new isoflavans were established by spectroscopic methods.

Original language	English
Pages (from-to)	1387-1389
Number of pages	3
Journal	Phytochemistry
Volume	36
Issue number	6
DOIs	https://doi.org/10.1016/S0031-9422(00)89728-9
State	Published - 1 Aug 1994
Externally published	Yes

Keywords

7-hydroxy-2′,3′,4′-trimethoxyisoflavan
8-methoxyvestitol
A. trigonus
antimicrobial.
astragaluquinone
Astragalus alexandrinus
Fabaceae
isoflavans
roots

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10.1016/S0031-9422(00)89728-9

Cite this

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title = "Antimicrobial isoflavans from Astragalus species",

abstract = "Two new antimicrobial isoflavans, 1-[(3R)-7,8-dimethoxybenzopyranyl]-4-hydroxybenzoquinone (astragaluquinone) and (3S)-7,1′-dihydroxy-8,3′-dimethoxyisoflavan (8-methoxyvestitol), and the known 7-hydroxy-2′,3′,4′-trimethoxyisoflavan were isolated from roots of Astragalus alexandrinus and A. trigonus. The structures of the new isoflavans were established by spectroscopic methods.",

keywords = "7-hydroxy-2′,3′,4′-trimethoxyisoflavan, 8-methoxyvestitol, A. trigonus, antimicrobial., astragaluquinone, Astragalus alexandrinus, Fabaceae, isoflavans, roots",

author = "El-Sebakhy, \{Nadia A.\} and Asaad, \{Aya M.\} and Abdallah, \{Rokia M.\} and Toaima, \{Soad M.\} and Abdel-Kader, \{Maged S.\} and Stermitz, \{Frank R.\}",

year = "1994",

month = aug,

day = "1",

doi = "10.1016/S0031-9422(00)89728-9",

language = "English",

volume = "36",

pages = "1387--1389",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier Ltd",

number = "6",

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TY - JOUR

T1 - Antimicrobial isoflavans from Astragalus species

AU - El-Sebakhy, Nadia A.

AU - Asaad, Aya M.

AU - Abdallah, Rokia M.

AU - Toaima, Soad M.

AU - Abdel-Kader, Maged S.

AU - Stermitz, Frank R.

PY - 1994/8/1

Y1 - 1994/8/1

N2 - Two new antimicrobial isoflavans, 1-[(3R)-7,8-dimethoxybenzopyranyl]-4-hydroxybenzoquinone (astragaluquinone) and (3S)-7,1′-dihydroxy-8,3′-dimethoxyisoflavan (8-methoxyvestitol), and the known 7-hydroxy-2′,3′,4′-trimethoxyisoflavan were isolated from roots of Astragalus alexandrinus and A. trigonus. The structures of the new isoflavans were established by spectroscopic methods.

AB - Two new antimicrobial isoflavans, 1-[(3R)-7,8-dimethoxybenzopyranyl]-4-hydroxybenzoquinone (astragaluquinone) and (3S)-7,1′-dihydroxy-8,3′-dimethoxyisoflavan (8-methoxyvestitol), and the known 7-hydroxy-2′,3′,4′-trimethoxyisoflavan were isolated from roots of Astragalus alexandrinus and A. trigonus. The structures of the new isoflavans were established by spectroscopic methods.

KW - 7-hydroxy-2′,3′,4′-trimethoxyisoflavan

KW - 8-methoxyvestitol

KW - A. trigonus

KW - antimicrobial.

KW - astragaluquinone

KW - Astragalus alexandrinus

KW - Fabaceae

KW - isoflavans

KW - roots

UR - https://www.scopus.com/pages/publications/0028484073

U2 - 10.1016/S0031-9422(00)89728-9

DO - 10.1016/S0031-9422(00)89728-9

M3 - Article

C2 - 7765429

AN - SCOPUS:0028484073

SN - 0031-9422

VL - 36

SP - 1387

EP - 1389

JO - Phytochemistry

JF - Phytochemistry

IS - 6

ER -

Antimicrobial isoflavans from Astragalus species

Abstract

Keywords

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