TY - JOUR
T1 - Anti-ulcerogenic Activity of Extract and Some Isolated Flavonoids from Desmostachia bipinnata (L.) Stapf
AU - Awaad, Amani S.
AU - Mohamed, Nawal H.
AU - Maitland, Derek J.
AU - Soliman, Gamal A.
N1 - Publisher Copyright:
© 2008, ACG Publications. All rights reserved.
PY - 2008/7/1
Y1 - 2008/7/1
N2 - Five main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Desmostachia bipinnata (L.)Stapf (Gramineae). They were i dent i fi ed as kaempf er ol (1), quercetin(2), quercetin-3-glucoside(3), trycin(4) and trycin-7-glucoside(5). The structure elucidation was based on UV, Electrospray ionization mass spectrometry (ESIMS), 1H and 13C NMR, proton-proton correlation spectroscopy (1H- 1H Cosy), distortionless enhancement by polarization transfer (DEPT), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlations spectrum (HMBC). The total extract (200 and 300 mg/kg) and two of the isolated compounds (trycin and trycin-7-glucoside.100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios; 68.31, 70.54, 77.39 and 78.93%, respectively.
AB - Five main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Desmostachia bipinnata (L.)Stapf (Gramineae). They were i dent i fi ed as kaempf er ol (1), quercetin(2), quercetin-3-glucoside(3), trycin(4) and trycin-7-glucoside(5). The structure elucidation was based on UV, Electrospray ionization mass spectrometry (ESIMS), 1H and 13C NMR, proton-proton correlation spectroscopy (1H- 1H Cosy), distortionless enhancement by polarization transfer (DEPT), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlations spectrum (HMBC). The total extract (200 and 300 mg/kg) and two of the isolated compounds (trycin and trycin-7-glucoside.100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios; 68.31, 70.54, 77.39 and 78.93%, respectively.
KW - Antiulcerogenic
KW - Desmostachia bipinnata (L.)Stapf
KW - quercetin and trycin-7-glucoside
KW - quercetin-3-glucoside
UR - http://www.scopus.com/inward/record.url?scp=85208128316&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85208128316
SN - 1307-6167
VL - 2
SP - 76
EP - 82
JO - Records of Natural Products
JF - Records of Natural Products
IS - 3
ER -