Anti-ulcerogenic Activity of Extract and Some Isolated Flavonoids from Desmostachia bipinnata (L.) Stapf

Amani S. Awaad; Nawal H. Mohamed; Derek J. Maitland; Gamal A. Soliman

Anti-ulcerogenic Activity of Extract and Some Isolated Flavonoids from Desmostachia bipinnata (L.) Stapf

Amani S. Awaad
, Nawal H. Mohamed
, Derek J. Maitland
, Gamal A. Soliman

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

Five main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Desmostachia bipinnata (L.)Stapf (Gramineae). They were i dent i fi ed as kaempf er ol (1), quercetin(2), quercetin-3-glucoside(3), trycin(4) and trycin-7-glucoside(5). The structure elucidation was based on UV, Electrospray ionization mass spectrometry (ESIMS), ¹H and ¹³C NMR, proton-proton correlation spectroscopy (¹H- ¹H Cosy), distortionless enhancement by polarization transfer (DEPT), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlations spectrum (HMBC). The total extract (200 and 300 mg/kg) and two of the isolated compounds (trycin and trycin-7-glucoside.100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios; 68.31, 70.54, 77.39 and 78.93%, respectively.

Original language	English
Pages (from-to)	76-82
Number of pages	7
Journal	Records of Natural Products
Volume	2
Issue number	3
State	Published - 1 Jul 2008
Externally published	Yes

Keywords

Antiulcerogenic
Desmostachia bipinnata (L.)Stapf
quercetin and trycin-7-glucoside
quercetin-3-glucoside

Cite this

@article{aaf700bf5da8476583c5de7e7bd40088,

title = "Anti-ulcerogenic Activity of Extract and Some Isolated Flavonoids from Desmostachia bipinnata (L.) Stapf",

abstract = "Five main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Desmostachia bipinnata (L.)Stapf (Gramineae). They were i dent i fi ed as kaempf er ol (1), quercetin(2), quercetin-3-glucoside(3), trycin(4) and trycin-7-glucoside(5). The structure elucidation was based on UV, Electrospray ionization mass spectrometry (ESIMS), 1H and 13C NMR, proton-proton correlation spectroscopy (1H- 1H Cosy), distortionless enhancement by polarization transfer (DEPT), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlations spectrum (HMBC). The total extract (200 and 300 mg/kg) and two of the isolated compounds (trycin and trycin-7-glucoside.100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios; 68.31, 70.54, 77.39 and 78.93\%, respectively.",

keywords = "Antiulcerogenic, Desmostachia bipinnata (L.)Stapf, quercetin and trycin-7-glucoside, quercetin-3-glucoside",

author = "Awaad, \{Amani S.\} and Mohamed, \{Nawal H.\} and Maitland, \{Derek J.\} and Soliman, \{Gamal A.\}",

year = "2008",

month = jul,

day = "1",

language = "English",

volume = "2",

pages = "76--82",

journal = "Records of Natural Products",

issn = "1307-6167",

publisher = "ACG Publications",

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TY - JOUR

T1 - Anti-ulcerogenic Activity of Extract and Some Isolated Flavonoids from Desmostachia bipinnata (L.) Stapf

AU - Awaad, Amani S.

AU - Mohamed, Nawal H.

AU - Maitland, Derek J.

AU - Soliman, Gamal A.

PY - 2008/7/1

Y1 - 2008/7/1

N2 - Five main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Desmostachia bipinnata (L.)Stapf (Gramineae). They were i dent i fi ed as kaempf er ol (1), quercetin(2), quercetin-3-glucoside(3), trycin(4) and trycin-7-glucoside(5). The structure elucidation was based on UV, Electrospray ionization mass spectrometry (ESIMS), 1H and 13C NMR, proton-proton correlation spectroscopy (1H- 1H Cosy), distortionless enhancement by polarization transfer (DEPT), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlations spectrum (HMBC). The total extract (200 and 300 mg/kg) and two of the isolated compounds (trycin and trycin-7-glucoside.100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios; 68.31, 70.54, 77.39 and 78.93%, respectively.

AB - Five main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Desmostachia bipinnata (L.)Stapf (Gramineae). They were i dent i fi ed as kaempf er ol (1), quercetin(2), quercetin-3-glucoside(3), trycin(4) and trycin-7-glucoside(5). The structure elucidation was based on UV, Electrospray ionization mass spectrometry (ESIMS), 1H and 13C NMR, proton-proton correlation spectroscopy (1H- 1H Cosy), distortionless enhancement by polarization transfer (DEPT), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlations spectrum (HMBC). The total extract (200 and 300 mg/kg) and two of the isolated compounds (trycin and trycin-7-glucoside.100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios; 68.31, 70.54, 77.39 and 78.93%, respectively.

KW - Antiulcerogenic

KW - Desmostachia bipinnata (L.)Stapf

KW - quercetin and trycin-7-glucoside

KW - quercetin-3-glucoside

UR - https://www.scopus.com/pages/publications/85208128316

M3 - Article

AN - SCOPUS:85208128316

SN - 1307-6167

VL - 2

SP - 76

EP - 82

JO - Records of Natural Products

JF - Records of Natural Products

IS - 3

ER -

Anti-ulcerogenic Activity of Extract and Some Isolated Flavonoids from Desmostachia bipinnata (L.) Stapf

Abstract

Keywords

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