TY - JOUR
T1 - Analyzing of L-tryptophan thermodynamics and its solubility in aqueous acetonitrile blends at diverse temperatures
AU - Saha, Avishek
AU - Ghosh, Sourav
AU - Ganai, Sintu
AU - Mukherjee, Puspal
AU - Mahali, Kalachand
AU - Saha, Bidyut
AU - Henaish, A. M.A.
AU - Guin, Partha Sarathi
AU - Alam, Perwez
AU - Roy, Sanjay
N1 - Publisher Copyright:
© 2023
PY - 2024/4
Y1 - 2024/4
N2 - This paper delves into an investigation of the solubility characteristics of L-tryptophan within binary solvent systems containing aqueous acetonitrile. The primary emphasis of the study revolves around assessments based on mole fractions. The study utilizes these solubility values to assess thermodynamic constraints, including solution entropies and solution transfer free energetics. The calculated thermodynamic energies are correlated with interaction parameters, including Gibbs free energies and entropies, pertaining to the transfer of L-tryptophanfrom water to binary solvent blends of acetonitrile and water. Mathematical expressions are utilized to determine the transfer Gibbs free energies for chemical interactions, and the consequent entropies are clarified within the framework of solvent-solvent interactions. To expound upon the stability of L-tryptophan within the water-acetonitrile mixed system, we investigate the energetic aspects related to the transfer of chemicals Gibbs free energies. Additionally, standard temperature (298.15 K) is employed to calculate various related physicochemical parameters of solute/solvent.
AB - This paper delves into an investigation of the solubility characteristics of L-tryptophan within binary solvent systems containing aqueous acetonitrile. The primary emphasis of the study revolves around assessments based on mole fractions. The study utilizes these solubility values to assess thermodynamic constraints, including solution entropies and solution transfer free energetics. The calculated thermodynamic energies are correlated with interaction parameters, including Gibbs free energies and entropies, pertaining to the transfer of L-tryptophanfrom water to binary solvent blends of acetonitrile and water. Mathematical expressions are utilized to determine the transfer Gibbs free energies for chemical interactions, and the consequent entropies are clarified within the framework of solvent-solvent interactions. To expound upon the stability of L-tryptophan within the water-acetonitrile mixed system, we investigate the energetic aspects related to the transfer of chemicals Gibbs free energies. Additionally, standard temperature (298.15 K) is employed to calculate various related physicochemical parameters of solute/solvent.
KW - Aqueous acetonitrile
KW - Chemical interactions
KW - L-tryptophan
KW - Solubility
KW - Thermodynamical constraints
UR - http://www.scopus.com/inward/record.url?scp=85184009471&partnerID=8YFLogxK
U2 - 10.1016/j.bpc.2024.107195
DO - 10.1016/j.bpc.2024.107195
M3 - Article
C2 - 38325036
AN - SCOPUS:85184009471
SN - 0301-4622
VL - 307
JO - Biophysical Chemistry
JF - Biophysical Chemistry
M1 - 107195
ER -