Analytical study of a Hepatitis B epidemic model using a discrete generalized nonsingular kernel

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Abstract

Hepatitis B is a worldwide viral infection that causes cirrhosis, hepatocellular cancer, the need for liver transplantation, and death. This work proposed a mathematical representation of Hepatitis B Virus (HBV) transmission traits emphasizing the significance of applied mathematics in comprehending how the disease spreads. The work used an updated Atangana-Baleanu fractional difference operator to create a fractional-order model of HBV. The qualitative assessment and well-posedness of the mathematical framework were looked at, and the global stability of equilibrium states as measured by the Volterra-type Lyapunov function was summarized. The exact answer was guaranteed to be unique using the Lipschitz condition. Additionally, there were various analyses of this new type of operator to support the operator’s efficacy. We observe that the explored discrete fractional operators will be χ2-increasing or decreasing in certain domains of the time scale Nj:= j, j + 1, … by looking at the fundamental characteristics of the proposed discrete fractional operators along with χ-monotonicity descriptions. For numerical simulations, solutions were constructed in the discrete generalized form of the Mittag-Leffler kernel, highlighting the impacts of the illness caused by numerous causes. The order of the fractional derivative had a significant influence on the dynamical process utilized to construct the HBV model. Researchers and policymakers can benefit from the suggested model’s ability to forecast infectious diseases such as HBV and take preventive action.

Original languageEnglish
Pages (from-to)16966-16997
Number of pages32
JournalAIMS Mathematics
Volume9
Issue number7
DOIs
StatePublished - 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • discrete Mittag-Leffler kernel
  • Hepatitis B model
  • Volterra-type Lyapunov function
  • χ-monotonicity investigations

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