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An In-vitro Analysis of the Antimicrobial Efficacy of a Novel Obturating Material for Primary Teeth

  • Lavanya Govindaraju
  • , Ganesh Jeevanandan
  • , Vishnu Priya Veeraraghavan
  • , Mohamed El-Sherbiny
  • , Ghala Basem Binshafi
  • , Shouq Khalid Alkharji
  • , Elaf Abdulrahmam Alhazza
  • , Rania A. Fouad
  • , Ateya Megahed Ibrahim
  • Saveetha Institute of Medical and Technical Sciences (Deemed to be University)
  • Almaarefa University
  • Mansoura University
  • Zagazig University

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The demand for an ideal obturating material in primary teeth with maximum antibacterial properties keeps escalating to increase the success rate of the root canal treatment in primary teeth. Hence the present study was conducted to determine the antimicrobial efficacy of the different concentrations of a novel obturating material. Different concentrations of the Novel Obturating Material was prepared using Calcium hydroxide, Zinc oxide cement and Metronidazole. It was tested for antimicrobial efficacy against S.mutans and E.faecalis using MHA for 24 hours at 37 ° C. The zone of inhibition was measured in millimetres after 24 hours. The values were subjected to statistical analysis. Maximum zone of inhibition against S.mutans was seen at 100 microliters with statistical significance at 3% 70–30 concentration and no difference was noted against E.faecalis. Comparison in between the groups revealed 1% 70–30 concentration of the Novel Obturating material at 100 microliters showed greater inhibition zone against S.mutans and no difference was noted against E.faecalis. 1% Metronidazole at 70–30 (calcium hydroxide- Zinc oxide) concentration of the Novel Obturating material at 100 microliters is effective against S.mutans and E.faecalis.

Original languageEnglish
Pages (from-to)110-114
Number of pages5
JournalJournal of International Dental and Medical Research
Volume17
Issue number1
StatePublished - 2024

Keywords

  • Child dentistry
  • Deciduous teeth
  • Novel
  • Obturating material
  • Pulpectomy

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