TY - JOUR
T1 - Aminoazoles in heterocyclic synthesis. Synthesis of some new pyrimidobenzimidazoles and pyrazolonopyridines as well as triazolo- tetrazolo- and pyrazolo-pyrimidines of pharmaceutical interest
AU - Kandeel, Ez El Din M.
AU - Hammouda, M.
AU - Metwally, M. A.
PY - 1996/4
Y1 - 1996/4
N2 - The reactivity of 3-cinnamoylindole, 3-cinnamoylantipyrine and 1-(3-methyl-1-phenyl-5-pyrazolon-4-yl)-4- antipyrin-4-yl)-prop-2-ene-1 one(la-c) towards 2- aminobenzimidazole, 3-amino-1,2,4-triazole, 5-aminotetrazole monohydrate, 5-amino-3-phenylpyrazole and 3-amino-1-phenyl-2- pyrazolin-5-one to give the fused heterocycles 2a-c, 4a,b, 5a,b, 8a,b, and 10a-c has been investigated. Structures of the synthesized compounds were confirmed by both the analytical and the spectral data (IR, UV and 1H NMR).
AB - The reactivity of 3-cinnamoylindole, 3-cinnamoylantipyrine and 1-(3-methyl-1-phenyl-5-pyrazolon-4-yl)-4- antipyrin-4-yl)-prop-2-ene-1 one(la-c) towards 2- aminobenzimidazole, 3-amino-1,2,4-triazole, 5-aminotetrazole monohydrate, 5-amino-3-phenylpyrazole and 3-amino-1-phenyl-2- pyrazolin-5-one to give the fused heterocycles 2a-c, 4a,b, 5a,b, 8a,b, and 10a-c has been investigated. Structures of the synthesized compounds were confirmed by both the analytical and the spectral data (IR, UV and 1H NMR).
KW - aminoazoles
KW - heterocycles
KW - pyr imidines
KW - pyrazolo-pyridines
KW - pyrimidobenzimidazoles
UR - https://www.scopus.com/pages/publications/0029798619
M3 - Article
C2 - 8913052
AN - SCOPUS:0029798619
SN - 0006-6648
VL - 135
SP - 232
EP - 235
JO - Bollettino Chimico Farmaceutico
JF - Bollettino Chimico Farmaceutico
IS - 4
ER -