A thorough and current study of miR-214-related targets in cancer

Bayu Indra Sukmana; Sulieman Ibraheem Shelash Al-Hawary; Munther Abosaooda; Mohaned Adile; Reena Gupta; Ebraheem Abdu Musad Saleh; Enas R. Alwaily; Hashem O. Alsaab; I. B. Sapaev; Yasser Fakri Mustafa

doi:10.1016/j.prp.2023.154770

A thorough and current study of miR-214-related targets in cancer

Bayu Indra Sukmana
, Sulieman Ibraheem Shelash Al-Hawary
, Munther Abosaooda
, Mohaned Adile
, Reena Gupta
, Ebraheem Abdu Musad Saleh
, Enas R. Alwaily
, Hashem O. Alsaab
, I. B. Sapaev
, Yasser Fakri Mustafa

Chemistry

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

Cancer is a complex genetic anomaly involving coding and non-coding transcript structural and expressive irregularities. A class of tiny non-coding RNAs known as microRNAs (miRNAs) regulates gene expression at the post-transcriptional level by binding only to messenger RNAs (mRNAs). Due to their capacity to target numerous genes, miRNAs have the potential to play a significant role in the development of tumors by controlling several biological processes, including angiogenesis, drug resistance, metastasis, apoptosis, proliferation, and drug resistance. According to several recent studies, miRNA-214 has been linked to the emergence and spread of tumors. The human genome's q24.3 arm contains the DNM3 gene, which is about 6 kb away and includes the microRNA-214. Its primary purpose was the induction of apoptosis in cancerous cells. The multifaceted and complex functions of miR-214 as a modulator in neoplastic conditions have been outlined in the current review.

Original language	English
Article number	154770
Journal	Pathology Research and Practice
Volume	249
DOIs	https://doi.org/10.1016/j.prp.2023.154770
State	Published - Sep 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer progression
MicroRNA-214
Non-coding RNA
Oncogenesis

Access to Document

10.1016/j.prp.2023.154770

Cite this

@article{b2df70c30ae642aeb00ef82b565d4598,

title = "A thorough and current study of miR-214-related targets in cancer",

abstract = "Cancer is a complex genetic anomaly involving coding and non-coding transcript structural and expressive irregularities. A class of tiny non-coding RNAs known as microRNAs (miRNAs) regulates gene expression at the post-transcriptional level by binding only to messenger RNAs (mRNAs). Due to their capacity to target numerous genes, miRNAs have the potential to play a significant role in the development of tumors by controlling several biological processes, including angiogenesis, drug resistance, metastasis, apoptosis, proliferation, and drug resistance. According to several recent studies, miRNA-214 has been linked to the emergence and spread of tumors. The human genome's q24.3 arm contains the DNM3 gene, which is about 6 kb away and includes the microRNA-214. Its primary purpose was the induction of apoptosis in cancerous cells. The multifaceted and complex functions of miR-214 as a modulator in neoplastic conditions have been outlined in the current review.",

keywords = "Cancer progression, MicroRNA-214, Non-coding RNA, Oncogenesis",

author = "Sukmana, \{Bayu Indra\} and Al-Hawary, \{Sulieman Ibraheem Shelash\} and Munther Abosaooda and Mohaned Adile and Reena Gupta and Saleh, \{Ebraheem Abdu Musad\} and Alwaily, \{Enas R.\} and Alsaab, \{Hashem O.\} and Sapaev, \{I. B.\} and Mustafa, \{Yasser Fakri\}",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2023",

month = sep,

doi = "10.1016/j.prp.2023.154770",

language = "English",

volume = "249",

journal = "Pathology Research and Practice",

issn = "0344-0338",

publisher = "Elsevier GmbH",

}

TY - JOUR

T1 - A thorough and current study of miR-214-related targets in cancer

AU - Sukmana, Bayu Indra

AU - Al-Hawary, Sulieman Ibraheem Shelash

AU - Abosaooda, Munther

AU - Adile, Mohaned

AU - Gupta, Reena

AU - Saleh, Ebraheem Abdu Musad

AU - Alwaily, Enas R.

AU - Alsaab, Hashem O.

AU - Sapaev, I. B.

AU - Mustafa, Yasser Fakri

PY - 2023/9

Y1 - 2023/9

N2 - Cancer is a complex genetic anomaly involving coding and non-coding transcript structural and expressive irregularities. A class of tiny non-coding RNAs known as microRNAs (miRNAs) regulates gene expression at the post-transcriptional level by binding only to messenger RNAs (mRNAs). Due to their capacity to target numerous genes, miRNAs have the potential to play a significant role in the development of tumors by controlling several biological processes, including angiogenesis, drug resistance, metastasis, apoptosis, proliferation, and drug resistance. According to several recent studies, miRNA-214 has been linked to the emergence and spread of tumors. The human genome's q24.3 arm contains the DNM3 gene, which is about 6 kb away and includes the microRNA-214. Its primary purpose was the induction of apoptosis in cancerous cells. The multifaceted and complex functions of miR-214 as a modulator in neoplastic conditions have been outlined in the current review.

AB - Cancer is a complex genetic anomaly involving coding and non-coding transcript structural and expressive irregularities. A class of tiny non-coding RNAs known as microRNAs (miRNAs) regulates gene expression at the post-transcriptional level by binding only to messenger RNAs (mRNAs). Due to their capacity to target numerous genes, miRNAs have the potential to play a significant role in the development of tumors by controlling several biological processes, including angiogenesis, drug resistance, metastasis, apoptosis, proliferation, and drug resistance. According to several recent studies, miRNA-214 has been linked to the emergence and spread of tumors. The human genome's q24.3 arm contains the DNM3 gene, which is about 6 kb away and includes the microRNA-214. Its primary purpose was the induction of apoptosis in cancerous cells. The multifaceted and complex functions of miR-214 as a modulator in neoplastic conditions have been outlined in the current review.

KW - Cancer progression

KW - MicroRNA-214

KW - Non-coding RNA

KW - Oncogenesis

UR - https://www.scopus.com/pages/publications/85170065708

U2 - 10.1016/j.prp.2023.154770

DO - 10.1016/j.prp.2023.154770

M3 - Review article

C2 - 37660658

AN - SCOPUS:85170065708

SN - 0344-0338

VL - 249

JO - Pathology Research and Practice

JF - Pathology Research and Practice

M1 - 154770

ER -

A thorough and current study of miR-214-related targets in cancer

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this