TY - JOUR
T1 - A comprehensive review of lncRNA CRNDE in cancer progression and pathology, with a specific glance at the epithelial-mesenchymal transition (EMT) process
AU - Jasim, Saade Abdalkareem
AU - Al-Hawary, Sulieman Ibraheem Shelash
AU - Hjazi, Ahmed
AU - Ahmad, Irfan
AU - Kaur, Irwanjot
AU - Kadhum, Wesam R.
AU - Alkhafaji, Adnan Taan
AU - Ghildiyal, Pallavi
AU - Jawad, Mohammed Abed
AU - Alsaadi, Salim B.
N1 - Publisher Copyright:
© 2024 Elsevier GmbH
PY - 2024/4
Y1 - 2024/4
N2 - It has been suggested that the long non-coding RNAs (lncRNAs), such as colorectal neoplasia differentially expressed (CRNDE), may contribute to the formation of human cancer. It is yet unknown, though, what therapeutic significance CRNDE expression has for different forms of cancer. CRNDE has recently been proposed as a possible diagnostic biomarker and prognostic pred for excellent specificity and sensitivity in cancer tissues and plasma. To provide the groundwork for potential future therapeutic uses of CRNDE, we briefly overview its biological action and related cancer-related pathways. Next, we mainly address the impact of CRNDE on the epithelial-mesenchymal transition (EMT). The epithelial-mesenchymal transition, or EMT, is an essential biological mechanism involved in the spread of cancer.
AB - It has been suggested that the long non-coding RNAs (lncRNAs), such as colorectal neoplasia differentially expressed (CRNDE), may contribute to the formation of human cancer. It is yet unknown, though, what therapeutic significance CRNDE expression has for different forms of cancer. CRNDE has recently been proposed as a possible diagnostic biomarker and prognostic pred for excellent specificity and sensitivity in cancer tissues and plasma. To provide the groundwork for potential future therapeutic uses of CRNDE, we briefly overview its biological action and related cancer-related pathways. Next, we mainly address the impact of CRNDE on the epithelial-mesenchymal transition (EMT). The epithelial-mesenchymal transition, or EMT, is an essential biological mechanism involved in the spread of cancer.
KW - Cancer progression
KW - CRNDE
KW - Epithelial-mesenchymal transition
KW - Long noncoding RNA
UR - https://www.scopus.com/pages/publications/85188153745
U2 - 10.1016/j.prp.2024.155229
DO - 10.1016/j.prp.2024.155229
M3 - Review article
C2 - 38484655
AN - SCOPUS:85188153745
SN - 0344-0338
VL - 256
JO - Pathology Research and Practice
JF - Pathology Research and Practice
M1 - 155229
ER -
