A besyian regularisation neural network approach for hepatitis B virus spread prediction and immune system therapy model

Ahmed M. Galal, Qusain Haider, Ali Hassan, Mubashar Arshad, Mohammad Mahtab Alam, Laila A. Al-Essa, Haile Habenom

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The primary aim of the article is to analyze the response of the human immune system when it encounters the hepatitis B virus. This is done using a mathematical system of differential equations. The differential equation system has six components, likely representing various aspects of the immune response or virus dynamics. A Bayesian regularization neural network has been presented in the process of training. These networks are employed to find solutions for different categories or scenarios related to hepatitis B infection. The Adams method is used to generate reference data sets. The back-propagated artificial neural network, based on Bayesian regularization, is trained and validated using the generated data. The data is divided into three sets: 90% for training and 5% each for testing and validation. The correctness and effectiveness of the proposed neural network model have been assessed using various evaluation metrics. The metrics have been used in this study are Mean Square Error (MSE), histogram errors, and regression plots. These measures provide support to the neural network to approximate the immune response to the hepatitis B virus.

Original languageEnglish
Article number23672
JournalScientific Reports
Volume14
Issue number1
DOIs
StatePublished - Dec 2024

Keywords

  • Bayesian regularization method
  • Hepatitis B virus
  • Immune system
  • Neural network, Numerical solutions

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