5-(Adamantan-1-yl)-3-[(4-fluoroanilino)methyl]-2,3-dihydro-1,3, 4-oxadiazole-2-thione

Abdul Malek S. Al-Tamimi; Ahmed M. Alafeefy; Ali A. El-Emam; Seik Weng Ng; Edward R.T. Tiekink

doi:10.1107/S1600536813009823

5-(Adamantan-1-yl)-3-[(4-fluoroanilino)methyl]-2,3-dihydro-1,3, 4-oxadiazole-2-thione

Abdul Malek S. Al-Tamimi
, Ahmed M. Alafeefy
, Ali A. El-Emam
, Seik Weng Ng
, Edward R.T. Tiekink

Pharmaceutical Chemistry

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

In the title compound, C₁₉H₂₂FN₃OS, the dihedral angle between the inclined oxadiazole and benzene rings is 52.7 (3)°. In the crystal, helical supramolecular chains along [100] are sustained by N - H⋯S hydrogen bonds supported by methylene-benzene C - H⋯π interactions. The crystal studied was an inversion twin with the fractional contribution of the minor component being 0.33 (14).

Original language	English
Pages (from-to)	o730
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	69
Issue number	5
DOIs	https://doi.org/10.1107/S1600536813009823
State	Published - May 2013

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title = "5-(Adamantan-1-yl)-3-[(4-fluoroanilino)methyl]-2,3-dihydro-1,3, 4-oxadiazole-2-thione",

abstract = "In the title compound, C19H22FN3OS, the dihedral angle between the inclined oxadiazole and benzene rings is 52.7 (3)°. In the crystal, helical supramolecular chains along [100] are sustained by N - H⋯S hydrogen bonds supported by methylene-benzene C - H⋯π interactions. The crystal studied was an inversion twin with the fractional contribution of the minor component being 0.33 (14).",

author = "Al-Tamimi, \{Abdul Malek S.\} and Alafeefy, \{Ahmed M.\} and El-Emam, \{Ali A.\} and Ng, \{Seik Weng\} and Tiekink, \{Edward R.T.\}",

year = "2013",

month = may,

doi = "10.1107/S1600536813009823",

language = "English",

volume = "69",

pages = "o730",

journal = "Acta Crystallographica Section E: Structure Reports Online",

issn = "1600-5368",

publisher = "International Union of Crystallography",

number = "5",

}

TY - JOUR

T1 - 5-(Adamantan-1-yl)-3-[(4-fluoroanilino)methyl]-2,3-dihydro-1,3, 4-oxadiazole-2-thione

AU - Al-Tamimi, Abdul Malek S.

AU - Alafeefy, Ahmed M.

AU - El-Emam, Ali A.

AU - Ng, Seik Weng

AU - Tiekink, Edward R.T.

PY - 2013/5

Y1 - 2013/5

N2 - In the title compound, C19H22FN3OS, the dihedral angle between the inclined oxadiazole and benzene rings is 52.7 (3)°. In the crystal, helical supramolecular chains along [100] are sustained by N - H⋯S hydrogen bonds supported by methylene-benzene C - H⋯π interactions. The crystal studied was an inversion twin with the fractional contribution of the minor component being 0.33 (14).

AB - In the title compound, C19H22FN3OS, the dihedral angle between the inclined oxadiazole and benzene rings is 52.7 (3)°. In the crystal, helical supramolecular chains along [100] are sustained by N - H⋯S hydrogen bonds supported by methylene-benzene C - H⋯π interactions. The crystal studied was an inversion twin with the fractional contribution of the minor component being 0.33 (14).

UR - https://www.scopus.com/pages/publications/84877263547

U2 - 10.1107/S1600536813009823

DO - 10.1107/S1600536813009823

M3 - Article

AN - SCOPUS:84877263547

SN - 1600-5368

VL - 69

SP - o730

JO - Acta Crystallographica Section E: Structure Reports Online

JF - Acta Crystallographica Section E: Structure Reports Online

IS - 5

ER -

5-(Adamantan-1-yl)-3-[(4-fluoroanilino)methyl]-2,3-dihydro-1,3, 4-oxadiazole-2-thione

Abstract

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