THE EFFECT OF ANISE (PIMPINELLA ANISUM ) ON CYP3A4 ENZYME ACTIVITY IN HUMAN LIVER MICROSOMS

Pharmacology, Toxicology and Pharmaceutical Science

1. Midazolam 100%
2. Salicylate Sodium 61%
3. Drug Interaction 53%
4. Methanol 38%
5. Prescription Drug 30%
6. Malignant Neoplasm 23%
7. Formate 23%
8. Phytochemical 23%
9. Drug Metabolizing Enzyme 23%
10. Adverse Event 15%
11. Hypericum perforatum 15%
12. Acetonitrile 15%
13. Reduced Nicotinamide Adenine Dinucleotide Phosphate 15%
14. IC50 15%
15. Cytochrome P450 15%
16. Diseases 15%
17. Chronic Disease 15%
18. Oxidoreductase 15%
19. Cardiovascular Disease 15%
20. Simvastatin 15%
21. Expectorant 15%
22. Dimethyl Sulfoxide 7%
23. Immunosuppressive Agent 7%
24. Antidepressant 7%
25. Pharmacokinetic 7%
26. Drug Safety 7%
27. Infection 7%
28. Potassium Phosphate 7%
29. Buffer 7%
30. Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor 7%
31. Sodium Dihydrogen Phosphate 7%
32. Gastrointestinal Disease 7%
33. Ammonium Acetate 7%
34. Carbamazepine 7%
35. Antimicrobial Agent 7%
36. Structure Activity Relationship 7%
37. Deionized Water 7%
38. Natural Product 7%
39. Adverse Drug Reaction 7%
40. Glucuronosyltransferase 7%
41. Spasmolytic Agent 7%
42. Nicotinamide Adenine Dinucleotide Phosphate 7%
43. Atorvastatin 7%
44. Drug Absorption 7%
45. Anticarcinogen 7%
46. Antioxidant 7%
47. Imatinib 7%
48. Diuretics 7%
49. Ketoconazole 7%