Effect of Nigella Sativa and thymoquinine in mitigating 5Flurouracil induced kidney dysfunction in wistar rats: Role of oxidative stress, apoptosis and MAPK pathway

Pharmacology, Toxicology and Pharmaceutical Science

1. Malignant Neoplasm 100%
2. Nigella sativa 100%
3. Mitogen Activated Protein Kinase 100%
4. Stress Activated Protein Kinase 100%
5. Wistar Rat 100%
6. Thymoquinone 36%
7. Nephrotoxicity 31%
8. Drug Resistance 21%
9. Glutathione 21%
10. Organ Toxicity 21%
11. Catalase 15%
12. Creatinine 15%
13. Reactive Oxygen Metabolite 15%
14. Antioxidant 15%
15. Therapeutic Window 15%
16. Cytokine 10%
17. Glutathione Reductase 10%
18. Kidney Injury 10%
19. Diseases 10%
20. Colorectal Carcinoma 10%
21. Breast Cancer 10%
22. Phosphotransferase 10%
23. Mitogen Activated Protein Kinase P38 10%
24. Inflammation 10%
25. Superoxide Dismutase 10%
26. Superoxide 5%
27. Glutathione Peroxidase 5%
28. Kidney Disease 5%
29. Adverse Event 5%
30. Antiinfective Agent 5%
31. Antiapoptotic 5%
32. Anticancer Drug 5%
33. Thymidylate Synthase 5%
34. Structure Activity Relationship 5%
35. Phenol 5%
36. Pathophysiology 5%
37. Acute Kidney Failure 5%
38. Antihypertensive Agent 5%
39. Cuprous Ion 5%
40. Antiulcer Agent 5%
41. Monotherapy 5%
42. Chrysin 5%
43. Lactate Dehydrogenase 5%
44. Protein Kinase 5%
45. Table Salt 5%
46. Natural Product 5%
47. Pyrimidine 5%
48. Hepatotoxicity 5%
49. Tumor Growth 5%
50. Leporidae 5%
51. Mucosa Inflammation 5%
52. Anticarcinogen 5%
53. Mitogen Activated Protein Kinase 3 5%
54. Carcinogenesis 5%
55. Emu 5%